15 November 2011

"Mercury Bob"

When I saw that we would be discussing MS, I knew I had to save my most amusing blog posting for last (I also had to get permission from a former Medical Director for the EMS agency I was working with at the time to talk about this.) I went on a poisoning call about ten years ago to a location near to Ft. Huachuca (About which I shall remain vague) for a patient we can call Bob (Which was, of course, not his name.) Bob had multiple sclerosis (MS) and was certain he could find a cure. He was not unknown to the local EMS providers and police. He had been living with MS his entire adult life and it was a crap-shoot who was taking care of whom between him and his mother in the trailer they lived in. This was in the days when the Internet was in its infancy, and Bob spent most of the time tying-up his phone line on his dial-up modem. He even hung up on the dispatcher because he needed to “Get back on the BBS to find out what to do” now that he was feeling ill from his “treatment” (Some of us will remember that the BBS system pre-dated the modern Internet.)

Since they couldn’t get back a hold of Bob, we went to his place as fast as possible with a Sheriff’s deputy escorting us. When we arrived, we found a makeshift chemistry lab, sandwich bags full of all kinds of herbs and powders, and Bob furiously banging away at his keyboard looking like he was about to seize. We managed to get him to stop the conspiracy talk long enough to tell us that he had developed a “cure” for MS that he was planning to market that involved, among other things, mega-doses of zinc. He said his cure was designed to “Chelate (Which he mispronounced) all of the toxic mercury from his body that was killing his nerves.” He also stated that he had recently had all of his dental fillings removed to “Get rid of the mercury poison.” When we asked him how he came up with his seaweed and zinc potion, he said he learned about it from a guy in India on a BBS group for MS patients (One of the firefighters on the scene tried to tell him that they probably didn’t have modems in India at that time and he got agitated.) He was extremely mad that his mother had called us and was convinced that the state he was in was related to the “Natural process of getting rid of mercury.”

We took him to a local hospital and he presented the entire way with really bizarre tremors that looked like mini-convulsions. I’ve never seen anything like it since and the receiving doc said he’d never seen it before. The grand irony was that Bob almost got his chelation therapy; it just would have been for the zinc he had poisoned himself with rather than the imaginary mercury. They flushed him with fluids and, I’m told, tested him for mercury levels which came back completely normal (Though Bob wasn’t buying it.) The frightening thing about all of this is that it was long before the Internet evolved. Imagine the barrage of false information a newly-diagnosed MS patient faces today. I did a search for “Multiple sclerosis” and “Cure” and the top hit was a pseudo-science website; searching for MS and “Natural therapy” brings back almost 49 million hits, most all involving quackery, and several that discuss that same nonsense that Bob was trying almost a decade ago…it’s frightening just how persistent misinformation can be!

3 comments:

  1. It's interesting that Bob was concerned with removing mercury to treat his MS. T-cell mediated autoimmunity (Type IV) is implicated in MS pathology. It may be that, somehow, an MS patient is immunized against their own brain. Specifically oligodendrocytes and myelin are thought to be the targets of an adaptive immune response. However it may happen, brain proteins are revealed to antigen presenting cells (APC's) which travel to the draining lymph nodes and produce activated Th cells which now recognize myelin. Under normal conditions the brain is hidden from the immune system by the blood brain barrier, but it is still "foreign" in the eyes of APC's. Certain events may lead to brain getting out of this sequestered area. Things like viral infections or traumatic brain injury might cause this to happen. Or it could be that a viral protein has cross-reactivity with myelin. Once activated, Th cells can easily cross the BBB and attack myelin. The Th cell recognizes its antigen, myelin, and secretes its cytokines which attract macrophages and other immune cells in an effort to remove the antigen. Consequently myelin is destroyed which produces the symptoms of MS.

    Now, back to mercury. Certain red tattoo inks contain a mercury salt which can causes T-cell mediated autoimmunity (Type IV). Dendritic cells recognize and process the mercury and show it to lymphocytes in a nearby lymph node. Activated Th cells now recognize the antigen in the tattoo in the skin. Cellular inflammation follows and the skin is ravaged in the process. Maybe there is some validity in his rationale?

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  2. Anything's possible! He's still at it, from what I'm told. Ten years later it doesn't sound like it has cured him, but who knows?!

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  3. I found it very interesting that Bob thought that ridding his body of mercury by taking out his filling would help get rid of toxins in his body and help cure his MS. I've heard many dentists say that silver amalgams are not harmful to people, and I found this article from Quackwatch that talks about false scare of mercury toxicity from amalgams.
    http://www.quackwatch.com/01QuackeryRelatedTopics/mercury.html
    From the article Bob must have heard about the study at the University of Calgary in Alberta, Canada where twelve amalgams were placed in sheep and the researchers found the sheep lost control of kidney function. However, what Bob may have not known are the parameters around the study which involved using amalgams that had an excess amount of mercury which made the fillings softer and more easy to wear when chewing, rubber dams where not used during the fillings, and levels of mercury where not measured before.
    So Bob needs to do consult with a qualified doctor on what MS is and how inflammation is involved.

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